NEODRON (STERILE OPTHALMIC SOLUTION)
(Dexamethsone + Neomycin)

COMPOSITION:
Each ml contains:
Dexamethasone phosphate: 1 mg.
Neomycin: 3.5 mg.
 

DESCRIPTION:
The ophthalmic preparation of NEODRON combines antibiotic offering broad spectrum antibacterial activity against sensitive organisms & with the anti-inflammatory activity of Dexamethsone for combating certain microbial infections of the eye(s).
 

INDICATIONS AND USAGE:
NEODRON ophthalmic solution and is indicated for steroid-responsive inflammatory ocular conditions for which a corticosteroid is indicated and where superficial bacterial ocular infection or a risk of bacterial ocular infection exists.
 

Ocular steroids are indicated in:
1- Inflammatory conditions of the palpebral and bulbar conjunctiva, cornea and anterior segment of the
globe where the inherent risk of steroid use in certain infective conjunctivitis is accepted to obtain a
diminution in edema and inflammation.
2- As preventive treatment in surgical operations or penetration of foreign bodies in the eyes.
NEODRON ophthalmic solution is used for treatment of eye - ear and nasal infections.
 

CONTRAINDICATIONS:
- Epithelial herpes simplex.
- Keratitis (dendritic keratitis).
- Vaccina.
- Varicella, and many other viral diseases of the cornea and conjunctiva.
- Fungal diseases of ocular structure.
- Hypersensitivity to a component of the medication.
 

ADVERSE REACTIONS:
The most frequent adverse reactions are lid itching and swelling, and conjunctival erythema. these reactions occur in less than 4% of patients.
 

The reactions due to the steroid component are:
- Elevation of intraocular pressure (IOP) with possible development of glaucoma.
- Infrequent optic nerve damage.
- Posterior subcapsular cataract formation.
- Delayed wound healing.
Secondary infection: The development of secondary infection has occurred after use of combinations containing steroids and antimicrobials. Fungal infections of the cornea are particularly prone to develop coincidentally with long-term applications of steroid. The possibility of invasion must be considered in any persistent corneal ulceration where steroid treatment has been used. Secondary bacterial ocular infection following suppression of host responses also occurs.
 

WARNINGS:
Sensitivity to topically neomycin may occur in some patients. If sensitivity reaction does occur, discontinue use.
Prolonged use of steroids may result in glaucoma, with damage to the optic nerve, defects in visual acuity and fields of vision, and posterior subcapsular cataract formation, intraocular pressure should be routinely monitored.
- Thinning of the cornea or sclera, perforations have been known to occur with use of topical steroids.
In acute purulent conditions of the eye, steroids may mask infection or enhance existing infection.
- To be used with caution during pregnancy & lactation.

DOSAGE AND ADMINISTRATION:
- Eyes infection: 1 – 2 drops / 4 - 6 hours instilled into the conjunctival sac(s).
- Ears infection: 2drops / 4 hours.
- Nasal infection: 1-2 drops / 8 hours. in the nostril.
Dosage and duration of the treatment should be followed according to the specialist.
 

HOW SUPPLIED:
As a sterile solution in 5 ml plastic dropper bottles.
 

STORAGE:
- Store at room temperature.
- protect from freezing.
- Keep out of the reach of children.
- On prescription only.
- Do not use for more than one month after the pack has been opened.